Anti-SGSH antibody (273-502) (STJ110447)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SGSH (273-502) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SGSH |
| Gene ID | 6448 |
| Uniprot ID | SPHM_HUMAN |
| Immunogen Region | 273-502 |
| Immunogen Sequence | DNGIPFPSGRTNLYWPGTAE PLLVSSPEHPKRWGQVSEAY VSLLDLTPTILDWFSIPYPS YAIFGSKTIHLTGRSLLPAL EAEPLWATVFGSQSHHEVTM SYPMRSVQHRHFRLVHNLNF KMPFPIDQDFYVSPTFQDLL NRTTAGQPTGWYKDLRHYYY RARWELYDRSRDPHETQNLA TDPRFAQLLEMLRDQLAKWQ WETHDPWVCAPDGVLEEKLS PQCQPLHNEL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 273-502 of human SGSH (NP_000190.1). |
Additional Info
| Post Translational Modifications | The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
| Function | Catalyzes a step in lysosomal heparan sulfate degradation. |
| Protein Name | N-Sulphoglucosamine SulphohydrolaseSulfoglucosamine SulfamidaseSulphamidase |
| Database Links | Reactome: R-HSA-2024096Reactome: R-HSA-2206307 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-N-Sulphoglucosamine Sulphohydrolase antibodyAnti-Sulfoglucosamine Sulfamidase antibodyAnti-Sulphamidase antibodyAnti-SGSH antibodyAnti-HSS antibody |
Information sourced from Uniprot.org