Anti-SGO2 antibody (681-730 aa) (STJ95641)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SGOL2 at the amino acid range 681-730
STJ95641
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General Information

Short DescriptionRabbit polyclonal anti-Shugoshin 2 (681-730 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC/IF/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeIHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSGO2
Gene ID151246
Uniprot IDSGO2_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SGOL2 at the amino acid range 681-730
Immunogen Region681-730 aa
SpecificitySgo2 Polyclonal Antibody detects endogenous levels of Sgo2 protein.

Additional Info

Protein Name Shugoshin 2
Shugoshin-2
Shugoshin-Like 2
Tripin
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-5663220
Reactome: R-HSA-68877
Reactome: R-HSA-9648025
Cellular Localisation Nucleus
Chromosome
Centromere
Kinetochore
During Meiosis I
Accumulates At Centromeres During Diplotene
And Colocalizes Differentially With The Cohesin Subunits Rad21 And Rec8 At Metaphase I Centromeres
Sgo2 And Rad21 Change Their Relative Distributions During Telophase I When Sister-Kinetochore Association Is Lost
During Meiosis Ii
It Shows A Striking Tension-Dependent Redistribution Within Centromeres Throughout Chromosome Congression During Prometaphase Ii
As It Does During Mitosis
In Hela Cells
Localizes At Centromeres Throughout Prophase Until Metaphase And Disappears At Anaphase
Centromeric Localization Requires The Presence Of Bub1 And Aukrb
Alternative Antibody Names Anti-Shugoshin 2 antibody
Anti-Shugoshin-2 antibody
Anti-Shugoshin-Like 2 antibody
Anti-Tripin antibody
Anti-SGO2 antibody
Anti-SGOL2 antibody

Information sourced from Uniprot.org

Citations

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