• Immunohistochemistry of rat kidney with Anti-SGK2 primary antibody (STJ502981) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-SGK2 antibody (377-427) (STJ502981)

SKU:
STJ502981-100

£441.50
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Host: Chicken
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Chicken polyclonal antibody anti-SGK2 (377-427) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgY
Purification: Affinity Purified
Concentration: 0.6 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:100
IF: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SGK2
Gene ID: 10110
Uniprot ID: SGK2_HUMAN
Immunogen Region: 377-427
Immunogen: Synthetic peptide taken within amino acid region 377-427 on human Sgk2 protein.
Tissue Specificity Highly expressed in liver, kidney and pancreas, and at lower levels in brain.
Post Translational Modifications Activated by phosphorylation on Ser-356 by an unknown kinase (may be mTORC2 but not confirmed), transforming it into a substrate for PDPK1 which then phosphorylates it on Thr-193.
Function Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.
Protein Name Serine/Threonine-Protein Kinase Sgk2
Serum/Glucocorticoid-Regulated Kinase 2
Database Links Reactome: R-HSA-2672351
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Serine/Threonine-Protein Kinase Sgk2 antibody
Anti-Serum/Glucocorticoid-Regulated Kinase 2 antibody
Anti-SGK2 antibody

Information sourced from Uniprot.org

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