Anti-SGCD antibody (61-290) (STJ29060)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SGCD (61-290) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SGCD |
| Gene ID | 6444 |
| Uniprot ID | SGCD_HUMAN |
| Immunogen Region | 61-290 |
| Immunogen Sequence | NFTIDGMGNLRITEKGLKLE GDSEFLQPLYAKEIQSRPGN ALYFKSARNVTVNILNDQTK VLTQLITGPKAVEAYGKKFE VKTVSGKLLFSADNNEVVVG AERLRVLGAEGTVFPKSIET PNVRADPFKELRLESPTRSL VMEAPKGVEINAEAGNMEAT CRTELRLESKDGEIKLDAAK IRLPRLPHGSYTPTGTRQKV FEICVCANGRLFLSQAGAGS TCQINTSVCL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 61-290 of human Delta-sarcoglycan (Delta-sarcoglycan (SGCD) ) (NP_000328.2). |
Additional Info
| Tissue Specificity | Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung. |
| Post Translational Modifications | Glycosylated. Disulfide bonds are present. |
| Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
| Protein Name | Delta-SarcoglycanDelta-Sg35 Kda Dystrophin-Associated Glycoprotein35dag |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | Cell MembraneSarcolemmaSingle-Pass Type Ii Membrane ProteinCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Delta-Sarcoglycan antibodyAnti-Delta-Sg antibodyAnti-35 Kda Dystrophin-Associated Glycoprotein antibodyAnti-35dag antibodyAnti-SGCD antibody |
Information sourced from Uniprot.org