• Western blot analysis of extracts of various cell lines, using SGCB antibody (STJ29059) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SGCB antibody (94-318) (STJ29059)

SKU:
STJ29059

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SGCB (94-318) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SGCB
Gene ID: 6443
Uniprot ID: SGCB_HUMAN
Immunogen Region: 94-318
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 94-318 of human SGCB (NP_000223.1).
Immunogen Sequence: PNGCDSMEFHESGLLRFKQV SDMGVIHPLYKSTVGGRRNE NLVITGNNQPIVFQQGTTKL SVENNKTSITSDIGMQFFDP RTQNILFSTDYETHEFHLPS GVKSLNVQKASTERITSNAT SDLNIKVDGRAIVRGNEGVF IMGKTIEFHMGGNMELKAEN SIILNGSVMVSTTRLPSSSS GDQLGSGDWVRYKLCMCADG TLFKVQVTSQNMGCQISDNP CGNTH
Tissue Specificity Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver.
Post Translational Modifications Disulfide bonds are present.
Function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Protein Name Beta-Sarcoglycan
Beta-Sg
43 Kda Dystrophin-Associated Glycoprotein
43dag
A3b
Cellular Localisation Cell Membrane
Sarcolemma
Single-Pass Type Ii Membrane Protein
Cytoplasm
Cytoskeleton
Alternative Antibody Names Anti-Beta-Sarcoglycan antibody
Anti-Beta-Sg antibody
Anti-43 Kda Dystrophin-Associated Glycoprotein antibody
Anti-43dag antibody
Anti-A3b antibody
Anti-SGCB antibody

Information sourced from Uniprot.org

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