Anti-SGCB antibody (94-318) (STJ29059)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SGCB (94-318) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SGCB |
| Gene ID | 6443 |
| Uniprot ID | SGCB_HUMAN |
| Immunogen Region | 94-318 |
| Immunogen Sequence | PNGCDSMEFHESGLLRFKQV SDMGVIHPLYKSTVGGRRNE NLVITGNNQPIVFQQGTTKL SVENNKTSITSDIGMQFFDP RTQNILFSTDYETHEFHLPS GVKSLNVQKASTERITSNAT SDLNIKVDGRAIVRGNEGVF IMGKTIEFHMGGNMELKAEN SIILNGSVMVSTTRLPSSSS GDQLGSGDWVRYKLCMCADG TLFKVQVTSQNMGCQISDNP CGNTH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 94-318 of human SGCB (NP_000223.1). |
Additional Info
| Tissue Specificity | Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver. |
| Post Translational Modifications | Disulfide bonds are present. |
| Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
| Protein Name | Beta-SarcoglycanBeta-Sg43 Kda Dystrophin-Associated Glycoprotein43dagA3b |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | Cell MembraneSarcolemmaSingle-Pass Type Ii Membrane ProteinCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Beta-Sarcoglycan antibodyAnti-Beta-Sg antibodyAnti-43 Kda Dystrophin-Associated Glycoprotein antibodyAnti-43dag antibodyAnti-A3b antibodyAnti-SGCB antibody |
Information sourced from Uniprot.org