Anti-SFXN3 antibody (1-80) (STJ114186)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SFXN3 (1-80) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SFXN3 |
| Gene ID | 81855 |
| Uniprot ID | SFXN3_HUMAN |
| Immunogen Region | 1-80 |
| Immunogen Sequence | MESKMGELPLDINIQEPRWD QSTFLGRARHFFTVTDPRNL LLSGAQLEASRNIVQNYRAG VVTPGITEDQLWRAKYVYDS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human SFXN3 (NP_112233.2). |
Additional Info
| Function | Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. |
| Protein Name | Sideroflexin-3 |
| Database Links | |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sideroflexin-3 antibodyAnti-SFXN3 antibody |
Information sourced from Uniprot.org