Anti-SF1 antibody [SQab30309] (STJ16103044)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
ImmunogenRecombinant protein of Human SF13.
General Information
| Short Description | Rabbit monoclonal anti-SF1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SQab30309 |
| Conjugation | Unconjugated |
| Purification | Purification with Protein A. |
| Formulation | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| Storage Instruction | Store at-20°C for up to 1 year. Minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SF1 |
| Gene ID | 7536 |
| Uniprot ID | SF01_HUMAN |
| Immunogen | Recombinant protein of Human SF13. |
Additional Info
| Post Translational Modifications | Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463. |
| Function | Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor. |
| Protein Name | Splicing Factor 1Mammalian Branch Point-Binding ProteinBbpMbbpTranscription Factor Zfm1Zinc Finger Gene In Men1 LocusZinc Finger Protein 162 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Splicing Factor 1 antibodyAnti-Mammalian Branch Point-Binding Protein antibodyAnti-Bbp antibodyAnti-Mbbp antibodyAnti-Transcription Factor Zfm1 antibodyAnti-Zinc Finger Gene In Men1 Locus antibodyAnti-Zinc Finger Protein 162 antibodyAnti-SF1 antibodyAnti-ZFM1 antibodyAnti-ZNF162 antibody |
Information sourced from Uniprot.org