Anti-SF1 antibody (48-97 aa) (STJ95752)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SF1 at the amino acid range 48-97
General Information
| Short Description | Rabbit polyclonal anti-Splicing factor 1 (48-97 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SF1 |
| Gene ID | 7536 |
| Uniprot ID | SF01_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human SF1 at the amino acid range 48-97 |
| Immunogen Region | 48-97 aa |
| Specificity | Splicing factor 1 Polyclonal Antibody detects endogenous levels of Splicing factor 1 protein. |
Additional Info
| Post Translational Modifications | Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463. |
| Function | Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor. |
| Protein Name | Splicing Factor 1Mammalian Branch Point-Binding ProteinBbpMbbpTranscription Factor Zfm1Zinc Finger Gene In Men1 LocusZinc Finger Protein 162 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Splicing Factor 1 antibodyAnti-Mammalian Branch Point-Binding Protein antibodyAnti-Bbp antibodyAnti-Mbbp antibodyAnti-Transcription Factor Zfm1 antibodyAnti-Zinc Finger Gene In Men1 Locus antibodyAnti-Zinc Finger Protein 162 antibodyAnti-SF1 antibodyAnti-ZFM1 antibodyAnti-ZNF162 antibody |
Information sourced from Uniprot.org