• Western blot analysis of various lysates, using SETD6 antibody (STJ11104783) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
  • Western blot analysis of various lysates, using SETD6 antibody (STJ11104783) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SETD6 antibody (310-473) [S4783RM] (STJ11104783)

SKU:
STJ11104783

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-N-Lysine Methyltransferase Setd6 (310-473) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4783RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SETD6
Gene ID: 79918
Uniprot ID: SETD6_HUMAN
Immunogen Region: 310-473
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 310-473 of human SETD6 (NP_001153777.1).
Immunogen Sequence: TADIQMVTVREAALQGTKTE AERHLVYERWDFLCKLEMVG EEGAFVIGREEVLTEEELTT TLKVLCMPAEEFRELKDQDG GGDDKREEGSLTITNIPKLK ASWRQLLQNSVLLTLQTYAT DLKTDQGLLSNKEVYAKLSW REQQALQVRYGQKMILHQLL ELTS
Post Translational Modifications Automethylated.Lys-39 and Lys-179 serve as the major automethylation sites.
Function Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity. Monomethylates 'Lys-8' of H2AZ (H2AZK8me1). Required for the maintenance of embryonic stem cell self-renewal. Methylates PAK4.
Protein Name N-Lysine Methyltransferase Setd6
Set Domain-Containing Protein 6
Database Links Reactome: R-HSA-3214841
Cellular Localisation Nucleus
Alternative Antibody Names Anti-N-Lysine Methyltransferase Setd6 antibody
Anti-Set Domain-Containing Protein 6 antibody
Anti-SETD6 antibody

Information sourced from Uniprot.org

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