Anti-SERPINB6 antibody (Internal) (STJ71589)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SERPINB6 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 40kDa band observed in Human Ovary lysates (calculated MW of 42.6kDa according to NP_004559.4). Recommended concentration: 0.1-.3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINB6 |
| Gene ID | 5269 |
| Uniprot ID | SPB6_HUMAN |
| Accession Number | NP_004559.4 |
| Immunogen Region | Internal |
| Immunogen Sequence | NWDEQFDKENTEER |
Additional Info
| Function | May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. |
| Protein Name | Serpin B6Cytoplasmic AntiproteinaseCapPeptidase Inhibitor 6Pi-6Placental Thrombin Inhibitor |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-75205 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Serpin B6 antibodyAnti-Cytoplasmic Antiproteinase antibodyAnti-Cap antibodyAnti-Peptidase Inhibitor 6 antibodyAnti-Pi-6 antibodyAnti-Placental Thrombin Inhibitor antibodyAnti-SERPINB6 antibodyAnti-PI6 antibodyAnti-PTI antibody |
Information sourced from Uniprot.org