Anti-SERPINB2 antibody (1-415) (STJ117492)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SERPINB2 (1-415) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINB2 |
| Gene ID | 5055 |
| Uniprot ID | PAI2_HUMAN |
| Immunogen Region | 1-415 |
| Immunogen Sequence | MEDLCVANTLFALNLFKHLA KASPTQNLFLSPWSISSTMA MVYMGSRGSTEDQMAKVLQF NEVGANAVTPMTPENFTSCG FMQQIQKGSYPDAILQAQAA DKIHSSFRSLSSAINASTGN YLLESVNKLFGEKSASFREE YIRLCQKYYSSEPQAVDFLE CAEEARKKINSWVKTQTKGK IPNLLPEGSVDGDTRMVLVN AVYFKGKWKTPFEKKLNGLY PFRVNSAQRTPVQMMYLRE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-415 of human SERPINB2 (NP_002566.1). |
Additional Info
| Post Translational Modifications | The signal sequence is not cleaved. |
| Function | Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. |
| Protein Name | Plasminogen Activator Inhibitor 2Pai-2Monocyte Arg-SerpinPlacental Plasminogen Activator InhibitorSerpin B2Urokinase Inhibitor |
| Database Links | Reactome: R-HSA-75205Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmSecretedExtracellular Space |
| Alternative Antibody Names | Anti-Plasminogen Activator Inhibitor 2 antibodyAnti-Pai-2 antibodyAnti-Monocyte Arg-Serpin antibodyAnti-Placental Plasminogen Activator Inhibitor antibodyAnti-Serpin B2 antibodyAnti-Urokinase Inhibitor antibodyAnti-SERPINB2 antibodyAnti-PAI2 antibodyAnti-PLANH2 antibody |
Information sourced from Uniprot.org