• Western blot analysis of extracts of various cell lines, using SERPINA6 antibody (STJ115569) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit.

Anti-SERPINA6 antibody (136-405) (STJ115569)

SKU:
STJ115569

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SERPINA6 (136-405) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SERPINA6
Gene ID: 866
Uniprot ID: CBG_HUMAN
Immunogen Region: 136-405
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 136-405 of human SERPINA6 (NP_001747.2).
Immunogen Sequence: SLELLESFSADIKHYYESEV LAMNFQDWATASRQINSYVK NKTQGKIVDLFSGLDSPAIL VLVNYIFFKGTWTQPFDLAS TREENFYVDETTVVKVPMML QSSTISYLHDAELPCQLVQM NYVGNGTVFFILPDKGKMNT VIAALSRDTINRWSAGLTSS QVDLYIPKVTISGVYDLGDV LEEMGIADLFTNQANFSRIT QDAQLKSSKVVHKAVLQLNE EGVDTAGSTGVTLNLTSKP
Tissue Specificity Plasma.synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.
Post Translational Modifications N-glycosylated.binds 5 oligosaccharide chains. Glycosylation in position Asn-260 is needed for steroid binding.
Function Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Protein Name Corticosteroid-Binding Globulin
Cbg
Serpin A6
Transcortin
Database Links Reactome: R-HSA-194002
Reactome: R-HSA-9757110
Cellular Localisation Secreted
Alternative Antibody Names Anti-Corticosteroid-Binding Globulin antibody
Anti-Cbg antibody
Anti-Serpin A6 antibody
Anti-Transcortin antibody
Anti-SERPINA6 antibody
Anti-CBG antibody

Information sourced from Uniprot.org

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