Anti-SERPINA6 antibody (136-405) (STJ115569)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SERPINA6 (136-405) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINA6 |
| Gene ID | 866 |
| Uniprot ID | CBG_HUMAN |
| Immunogen Region | 136-405 |
| Immunogen Sequence | SLELLESFSADIKHYYESEV LAMNFQDWATASRQINSYVK NKTQGKIVDLFSGLDSPAIL VLVNYIFFKGTWTQPFDLAS TREENFYVDETTVVKVPMML QSSTISYLHDAELPCQLVQM NYVGNGTVFFILPDKGKMNT VIAALSRDTINRWSAGLTSS QVDLYIPKVTISGVYDLGDV LEEMGIADLFTNQANFSRIT QDAQLKSSKVVHKAVLQLNE EGVDTAGSTGVTLNLTSKP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 136-405 of human SERPINA6 (NP_001747.2). |
Additional Info
| Tissue Specificity | Plasma.synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. |
| Post Translational Modifications | N-glycosylated.binds 5 oligosaccharide chains. Glycosylation in position Asn-260 is needed for steroid binding. |
| Function | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| Protein Name | Corticosteroid-Binding GlobulinCbgSerpin A6Transcortin |
| Database Links | Reactome: R-HSA-194002Reactome: R-HSA-9757110 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Corticosteroid-Binding Globulin antibodyAnti-Cbg antibodyAnti-Serpin A6 antibodyAnti-Transcortin antibodyAnti-SERPINA6 antibodyAnti-CBG antibody |
Information sourced from Uniprot.org