Anti-SERPINA12 antibody (Internal) (STJ71574)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ71574-100
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General Information

Short DescriptionGoat polyclonal antibody anti-SERPINA12 (Internal) is suitable for use in ELISA and Western Blot research applications.
ApplicationsPep-ELISA/WB
HostGoat
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:32000.
WB: Approx 48kDa band observed in Human Adipose lysates (calculated MW of 47.2kDa according to NP_776249.1). Recommended concentration: 0.3-1ยตg/ml.
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20ยฐC on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolSERPINA12
Gene ID145264
Uniprot IDSPA12_HUMAN
Accession NumberNP_776249.1
Immunogen RegionInternal
Immunogen SequenceRARWKHEFDPNVTK

Additional Info

Post Translational Modifications Glycosylation slightly decreases affinity for heparin, but otherwise has no significant effect on KLK7 inhibitory activity or thermal stability of the protein.
Function Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues.
Protein Name Serpin A12
Ol-64
Visceral Adipose Tissue-Derived Serine Protease Inhibitor
Vaspin
Visceral Adipose-Specific Serpin
Cellular Localisation Secreted
Alternative Antibody Names Anti-Serpin A12 antibody
Anti-Ol-64 antibody
Anti-Visceral Adipose Tissue-Derived Serine Protease Inhibitor antibody
Anti-Vaspin antibody
Anti-Visceral Adipose-Specific Serpin antibody
Anti-SERPINA12 antibody

Information sourced from Uniprot.org

Citations

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