Anti-SERF1A/SERF1B antibody (10-60 aa) (STJ198104)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SERF1 at the amino acid range 10-60
General Information
| Short Description | Rabbit polyclonal anti-Small EDRK-rich factor 1 (10-60 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SERF1A.SERF1B |
| Gene ID | 728492/8293 |
| Uniprot ID | SERF1_HUMAN |
| Immunogen | Synthesized peptide derived from the human SERF1 at the amino acid range 10-60 |
| Immunogen Region | 10-60 aa |
| Specificity | This antibody detects endogenous levels of human SERF1 |
Additional Info
| Function | Positive regulator of amyloid protein aggregation and proteotoxicity. Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, driving them into compact formations preceding the formation of aggregates. |
| Protein Name | Small Edrk-Rich Factor 1Protein 4f5H4f5Sma Modifier 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolNucleus |
| Alternative Antibody Names | Anti-Small Edrk-Rich Factor 1 antibodyAnti-Protein 4f5 antibodyAnti-H4f5 antibodyAnti-Sma Modifier 1 antibodyAnti-SERF1A antibodyAnti-FAM2A antibodyAnti-SERF1 antibodyAnti-SMAM1.SERF1B antibodyAnti-FAM2B antibodyAnti-SERF1 antibodyAnti-SMAM1 antibody |
Information sourced from Uniprot.org