• Western blot analysis of lysates from HeLa, HUVEC, and MCF-7 cells, using SEPT7 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HUVECcells using SEPT7 antibody.
  • Western blot analysis of various cells using Septin 7 Polyclonal Antibody

Anti-SEPTIN7 antibody (350-399 aa) (STJ95616)

SKU:
STJ95616

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Septin-7 (350-399 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SEPTIN7
Gene ID: 989
Uniprot ID: SEPT7_HUMAN
Immunogen Region: 350-399 aa
Specificity: Septin 7 Polyclonal Antibody detects endogenous levels of Septin 7 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SEPT7 at the amino acid range 350-399
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
Protein Name Septin-7
Cdc10 Protein Homolog
Database Links Reactome: R-HSA-5687128
Cellular Localisation Cytoplasm
Chromosome
Centromere
Kinetochore
Cytoskeleton
Spindle
Cleavage Furrow
Midbody
Cilium Axoneme
Cell Projection
Cilium
Flagellum
Distributed Throughout The Cytoplasm In Prometaphase Cells
Associated With The Spindle During Metaphase
Associated With The Central Spindle And At The Cleavage Furrow In Anaphase Cells
Detected At The Midbody In Telophase
Associated With Actin Stress Fibers
Found In The Sperm Annulus
Alternative Antibody Names Anti-Septin-7 antibody
Anti-Cdc10 Protein Homolog antibody
Anti-SEPTIN7 antibody
Anti-CDC10 antibody
Anti-SEPT7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance