Anti-SEPTIN7 antibody (350-399 aa) (STJ95616)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SEPT7 at the amino acid range 350-399
General Information
| Short Description | Rabbit polyclonal anti-Septin-7 (350-399 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:50-300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEPTIN7 |
| Gene ID | 989 |
| Uniprot ID | SEPT7_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human SEPT7 at the amino acid range 350-399 |
| Immunogen Region | 350-399 aa |
| Specificity | Septin 7 Polyclonal Antibody detects endogenous levels of Septin 7 protein. |
Additional Info
| Function | Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. |
| Protein Name | Septin-7Cdc10 Protein Homolog |
| Database Links | Reactome: R-HSA-5687128 |
| Cellular Localisation | CytoplasmChromosomeCentromereKinetochoreCytoskeletonSpindleCleavage FurrowMidbodyCilium AxonemeCell ProjectionCiliumFlagellumDistributed Throughout The Cytoplasm In Prometaphase CellsAssociated With The Spindle During MetaphaseAssociated With The Central Spindle And At The Cleavage Furrow In Anaphase CellsDetected At The Midbody In TelophaseAssociated With Actin Stress FibersFound In The Sperm Annulus |
| Alternative Antibody Names | Anti-Septin-7 antibodyAnti-Cdc10 Protein Homolog antibodyAnti-SEPTIN7 antibodyAnti-CDC10 antibodyAnti-SEPT7 antibody |
Information sourced from Uniprot.org