Anti-SEPTIN6 antibody (223-272 aa) (STJ95615)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SEPT6 at the amino acid range 223-272
General Information
| Short Description | Rabbit polyclonal anti-Septin-6 (223-272 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEPTIN6 |
| Gene ID | 23157 |
| Uniprot ID | SEPT6_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human SEPT6 at the amino acid range 223-272 |
| Immunogen Region | 223-272 aa |
| Specificity | Septin 6 Polyclonal Antibody detects endogenous levels of Septin 6 protein. |
Additional Info
| Function | Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. |
| Protein Name | Septin-6 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSpindleChromosomeCentromereKinetochoreCleavage FurrowMidbodyCell ProjectionCiliumFlagellumIn Metaphase CellsLocalized Within The Microtubule SpindleAt The Metaphase PlateIn Close Apposition To The Kinetochores Of The Congressed ChromosomesIn Cells Undergoing CytokinesisLocalized To The MidbodyThe Ingressing Cleavage FurrowAnd The Central SpindleFound In The Sperm Annulus |
| Alternative Antibody Names | Anti-Septin-6 antibodyAnti-SEPTIN6 antibodyAnti-KIAA0128 antibodyAnti-SEP2 antibodyAnti-SEPT6 antibody |
Information sourced from Uniprot.org