Anti-SEPT5 antibody (1-369) (STJ114819)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SEPT5 (1-369) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IHC-P:1:100-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEPTIN5 |
| Gene ID | 5413 |
| Uniprot ID | SEPT5_HUMAN |
| Immunogen Region | 1-369 |
| Immunogen Sequence | MSTGLRYKSKLATPEDKQDI DKQYVGFATLPNQVHRKSVK KGFDFTLMVAGESGLGKSTL VHSLFLTDLYKDRKLLSAEE RISQTVEILKHTVDIEEKGV KLKLTIVDTPGFGDAVNNTE CWKPITDYVDQQFEQYFRDE SGLNRKNIQDNRVHCCLYFI SPFGHGLRPVDVGFMKALHE KVNIVPLIAKADCLVPSEIR KLKERIREEIDKFGIHVYQF PECDSDEDEDFKQQDRELK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human Septin 5 (NP_002679.2). |
Additional Info
| Tissue Specificity | Expressed at high levels in the CNS, as well as in heart and platelets (at protein level). |
| Post Translational Modifications | Phosphorylated by DYRK1A. In platelets, phosphorylated in response to thrombin, phorbol-12-myristate-13-acetate and collagen. |
| Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion. |
| Protein Name | Septin-5Cell Division Control-Related Protein 1Cdcrel-1Peanut-Like Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonIn PlateletsFound In Areas Surrounding Alpha-Granules |
| Alternative Antibody Names | Anti-Septin-5 antibodyAnti-Cell Division Control-Related Protein 1 antibodyAnti-Cdcrel-1 antibodyAnti-Peanut-Like Protein 1 antibodyAnti-SEPTIN5 antibodyAnti-PNUTL1 antibodyAnti-SEPT5 antibody |
Information sourced from Uniprot.org