Anti-Semaphorin-3A antibody (Central Region) (STJA0041391)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSemaphorin 3A synthetic peptide (coupled to carrier protein) corresponding to amino acids in the central region of human Sema3A. The sequence used is highly conserved in rat and mouse Sema3A, and has low homology to other semaphorin family members.
General Information
| Short Description | Rabbit polyclonal anti-Semaphorin-3A (Central Region) for use in ELISA, WB, ICC and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Antigen Affinity Purified |
| Dilution Range | WB 1:1000IHC 6:00ICC 1:100 |
| Formulation | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction | Storage at-20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at-20°C. |
Target Information
| Gene Symbol | SEMA3A |
| Gene ID | 10371 |
| Uniprot ID | SEM3A_HUMAN |
| Immunogen | Semaphorin 3A synthetic peptide (coupled to carrier protein) corresponding to amino acids in the central region of human Sema3A. The sequence used is highly conserved in rat and mouse Sema3A, and has low homology to other semaphorin family members. |
| Immunogen Region | Central Region |
| Immunogen Sequence | Human |
| Specificity | The antibody detects a 95kDa* protein corresponding to the apparent molecular mass of Sema3A on SDS-PAGE immunoblots of human recombinant Sema3A and neonatal rat brain lysates. |
Additional Info
| Tissue Specificity | Expressed in the dorsal root ganglia. |
| Function | Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1. |
| Protein Name | Semaphorin-3aSemaphorin IiiSema Iii |
| Database Links | Reactome: R-HSA-399954Reactome: R-HSA-399955Reactome: R-HSA-399956 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Semaphorin-3a antibodyAnti-Semaphorin Iii antibodyAnti-Sema Iii antibodyAnti-SEMA3A antibodyAnti-SEMAD antibody |
Information sourced from Uniprot.org