| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SEMA4C (749-833) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SEMA4C |
| Gene ID: |
54910 |
| Uniprot ID: |
SEM4C_HUMAN |
| Immunogen Region: |
749-833 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 749-833 of human SEMA4C (NP_060259.4). |
| Immunogen Sequence: |
HARCQPGGGPPSPPPGIPGQ PLPSPTRLHLGGGRNSNANG YVRLQLGGEDRGGLGHPLPE LADELRRKLQQRQPLPDSNP EESSV |
| Function | Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. |
| Protein Name | Semaphorin-4c |
| Cellular Localisation | Postsynaptic Density MembraneSingle-Pass Type I Membrane ProteinCytoplasmic VesicleSecretory VesicleSynaptic Vesicle Membrane |
| Alternative Antibody Names | Anti-Semaphorin-4c antibodyAnti-SEMA4C antibodyAnti-KIAA1739 antibodyAnti-SEMAI antibodyAnti-UNQ5855 antibodyAnti-PRO34487 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
