Anti-SEMA4C antibody (749-833) (STJ110524)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SEMA4C (749-833) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEMA4C |
| Gene ID | 54910 |
| Uniprot ID | SEM4C_HUMAN |
| Immunogen Region | 749-833 |
| Immunogen Sequence | HARCQPGGGPPSPPPGIPGQ PLPSPTRLHLGGGRNSNANG YVRLQLGGEDRGGLGHPLPE LADELRRKLQQRQPLPDSNP EESSV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 749-833 of human SEMA4C (NP_060259.4). |
Additional Info
| Function | Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. |
| Protein Name | Semaphorin-4c |
| Database Links | |
| Cellular Localisation | Postsynaptic Density MembraneSingle-Pass Type I Membrane ProteinCytoplasmic VesicleSecretory VesicleSynaptic Vesicle Membrane |
| Alternative Antibody Names | Anti-Semaphorin-4c antibodyAnti-SEMA4C antibodyAnti-KIAA1739 antibodyAnti-SEMAI antibodyAnti-UNQ5855 antibodyAnti-PRO34487 antibody |
Information sourced from Uniprot.org