Anti-SEMA3A antibody (582-771) [S4751RM] (STJ11104751)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Semaphorin-3a (582-771) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4751RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:2000-1:20000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEMA3A |
| Gene ID | 10371 |
| Uniprot ID | SEM3A_HUMAN |
| Immunogen Region | 582-771 |
| Immunogen Sequence | ERIIYGVENSSTFLECSPKS QRALVYWQFQRRNEERKEEI RVDDHIIRTDQGLLLRSLQQ KDSGNYLCHAVEHGFIQTLL KVTLEVIDTEHLEELLHKDD DGDGSKTKEMSNSMTPSQKV WYRDFMQLINHPNLNTMDEF CEQVWKRDRKQRRQRPGHTP GNSNKWKHLQENKKGRNRRT HEFERAPRSV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 582-771 of human Semaphorin 3A (NP_006071.1). |
Additional Info
| Tissue Specificity | Expressed in the dorsal root ganglia. |
| Function | Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1. |
| Protein Name | Semaphorin-3aSemaphorin IiiSema Iii |
| Database Links | Reactome: R-HSA-399954Reactome: R-HSA-399955Reactome: R-HSA-399956 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Semaphorin-3a antibodyAnti-Semaphorin Iii antibodyAnti-Sema Iii antibodyAnti-SEMA3A antibodyAnti-SEMAD antibody |
Information sourced from Uniprot.org