| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-L-selectin (91-140 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 IHC-P 1:50-300 ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SELL |
| Gene ID: | 6402 |
| Uniprot ID: | LYAM1_HUMAN |
| Immunogen Region: | 91-140 aa |
| Specificity: | L-Selectin Polyclonal Antibody detects endogenous levels of L-Selectin protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human SELL at the amino acid range 91-140 |
| Post Translational Modifications | N-glycosylated. |
| Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. |
| Protein Name | L-Selectin Cd62 Antigen-Like Family Member L Leukocyte Adhesion Molecule 1 Lam-1 Leukocyte Surface Antigen Leu-8 Leukocyte-Endothelial Cell Adhesion Molecule 1 Lecam1 Lymph Node Homing Receptor Tq1 Gp90-Mel Cd Antigen Cd62l |
| Database Links | Reactome: R-HSA-198933 Reactome: R-HSA-202733 Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-L-Selectin antibody Anti-Cd62 Antigen-Like Family Member L antibody Anti-Leukocyte Adhesion Molecule 1 antibody Anti-Lam-1 antibody Anti-Leukocyte Surface Antigen Leu-8 antibody Anti-Leukocyte-Endothelial Cell Adhesion Molecule 1 antibody Anti-Lecam1 antibody Anti-Lymph Node Homing Receptor antibody Anti-Tq1 antibody Anti-Gp90-Mel antibody Anti-Cd Antigen Cd62l antibody Anti-SELL antibody Anti-LNHR antibody Anti-LYAM1 antibody |
Information sourced from Uniprot.org