Anti-SELENOS antibody (STJA0006833)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SELS
General Information
| Short Description | Rabbit polyclonal anti-Selenoprotein S for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SELENOS |
| Gene ID | 55829 |
| Uniprot ID | SELS_HUMAN |
| Immunogen | Synthesized peptide derived from human SELS |
| Specificity | This antibody detects endogenous levels of SELS at Human, Mouse, Rat |
Additional Info
| Function | Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination. |
| Protein Name | Selenoprotein SSelsVcp-Interacting Membrane Protein |
| Database Links | Reactome: R-HSA-8866654 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Selenoprotein S antibodyAnti-Sels antibodyAnti-Vcp-Interacting Membrane Protein antibodyAnti-SELENOS antibodyAnti-SELS antibodyAnti-VIMP antibodyAnti-AD-015 antibodyAnti-SBBI8 antibody |
Information sourced from Uniprot.org