Anti-SELENBP1 antibody [3H1] (STJA0032744)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenFull length human recombinant protein of human SELENBP1 produced in 293T cell.
General Information
| Short Description | Mouse monoclonal anti-SELENBP1 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3H1 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4Β°C short term. Aliquot and store at-20Β°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SELENBP1 |
| Gene ID | 8991 |
| Uniprot ID | SBP1_HUMAN |
| Immunogen | Full length human recombinant protein of human SELENBP1 produced in 293T cell. |
Additional Info
| Tissue Specificity | Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. |
| Post Translational Modifications | Phosphorylated. The N-terminus is blocked. |
| Function | Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport. |
| Protein Name | Methanethiol OxidaseMto56 Kda Selenium-Binding ProteinSbp56Sp56Selenium-Binding Protein 1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytosolMembranePeripheral Membrane ProteinMay Associate With Golgi MembraneMay Associate With The Membrane Of Autophagosomes |
| Alternative Antibody Names | Anti-Methanethiol Oxidase antibodyAnti-Mto antibodyAnti-56 Kda Selenium-Binding Protein antibodyAnti-Sbp56 antibodyAnti-Sp56 antibodyAnti-Selenium-Binding Protein 1 antibodyAnti-SELENBP1 antibodyAnti-SBP antibody |
Information sourced from Uniprot.org