| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SELENBP1 (243-472) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SELENBP1 |
| Gene ID: |
8991 |
| Uniprot ID: |
SBP1_HUMAN |
| Immunogen Region: |
243-472 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 243-472 of human SELENBP1 (NP_003935.2). |
| Immunogen Sequence: |
SLKDGLIPLEIRFLHNPDAA QGFVGCALSSTIQRFYKNEG GTWSVEKVIQVPPKKVKGWL LPEMPGLITDILLSLDDRFL YFSNWLHGDLRQYDISDPQR PRLTGQLFLGGSIVKGGPVQ VLEDEELKSQPEPLVVKGKR VAGGPQMIQLSLDGKRLYIT TSLYSAWDKQFYPDLIREGS VMLQVDVDTVKGGLKLNPNF LVDFGKEPLGPALAHELRYP GGDCSSDIWI |
| Tissue Specificity | Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. |
| Post Translational Modifications | Phosphorylated. The N-terminus is blocked. |
| Function | Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport. |
| Protein Name | Methanethiol OxidaseMto56 Kda Selenium-Binding ProteinSbp56Sp56Selenium-Binding Protein 1 |
| Cellular Localisation | NucleusCytoplasmCytosolMembranePeripheral Membrane ProteinMay Associate With Golgi MembraneMay Associate With The Membrane Of Autophagosomes |
| Alternative Antibody Names | Anti-Methanethiol Oxidase antibodyAnti-Mto antibodyAnti-56 Kda Selenium-Binding Protein antibodyAnti-Sbp56 antibodyAnti-Sp56 antibodyAnti-Selenium-Binding Protein 1 antibodyAnti-SELENBP1 antibodyAnti-SBP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
