Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Dog/Cow |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-SEL1L (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
WB-1-3µg/mlELISA-antibody detection limit dilution 1:1000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
SEL1L |
Gene ID: |
6400 |
Uniprot ID: |
SE1L1_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_005056.3 |
Immunogen Sequence: |
TAYNSYKDGDYN |
Post Translational Modifications | N-glycosylated. |
Function | Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling. |
Protein Name | Protein Sel-1 Homolog 1Suppressor Of Lin-12-Like Protein 1Sel-1l |
Database Links | Reactome: R-HSA-1912420Reactome: R-HSA-382556Reactome: R-HSA-5358346Reactome: R-HSA-5362768Reactome: R-HSA-5678895Reactome: R-HSA-901032 |
Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Protein Sel-1 Homolog 1 antibodyAnti-Suppressor Of Lin-12-Like Protein 1 antibodyAnti-Sel-1l antibodyAnti-SEL1L antibodyAnti-TSA305 antibodyAnti-UNQ128 antibodyAnti-PRO1063 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance