Anti-SEC61A antibody [R06-1S9] (STJA0036849)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human SEC61A
General Information
| Short Description | Rabbit monoclonal anti-SEC61A for use in WB, IHC-P, ICC, IF, IP and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/IP/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-1S9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:50FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SEC61A2 |
| Gene ID | 55176 |
| Uniprot ID | S61A2_HUMAN |
| Immunogen | A synthesized peptide derived from human SEC61A |
Additional Info
| Function | Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. |
| Protein Name | Protein Transport Protein Sec61 Subunit Alpha Isoform 2Sec61 Alpha-2 |
| Database Links | Reactome: R-HSA-1236974Reactome: R-HSA-1799339 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein Transport Protein Sec61 Subunit Alpha Isoform 2 antibodyAnti-Sec61 Alpha-2 antibodyAnti-SEC61A2 antibody |
Information sourced from Uniprot.org