Anti-SEC24D antibody (1-100) [S4196RM] (STJ11104196)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Protein Transport Protein Sec24d (1-100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4196RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEC24D |
| Gene ID | 9871 |
| Uniprot ID | SC24D_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MSQQGYVATPPYSQPQPGIG LSPPHYGHYGDPSHTASPTG MMKPAGPLGATATRGMLPPG PPPPGPHQFGQNGAHATGHP PQRFPGPPPVNNVASSHAPY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SEC24D (NP_001304995.1). |
Additional Info
| Tissue Specificity | Ubiquitously expressed, with higher amounts in placenta, pancreas, heart and liver. |
| Function | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24C may have a different specificity compared to SEC24A and SEC24B. May more specifically package GPI-anchored proteins through the cargo receptor TMED10. May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5. |
| Protein Name | Protein Transport Protein Sec24dSec24-Related Protein D |
| Database Links | Reactome: R-HSA-1655829Reactome: R-HSA-204005Reactome: R-HSA-2132295Reactome: R-HSA-5694530Reactome: R-HSA-9705671Reactome: R-HSA-983170 |
| Cellular Localisation | Cytoplasmic VesicleCopii-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideEndoplasmic Reticulum MembraneCytoplasmCytosol |
| Alternative Antibody Names | Anti-Protein Transport Protein Sec24d antibodyAnti-Sec24-Related Protein D antibodyAnti-SEC24D antibodyAnti-KIAA0755 antibody |
Information sourced from Uniprot.org