Anti-SEC23A antibody [R06-7P5] (STJA0036706)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human SEC23
General Information
| Short Description | Rabbit monoclonal anti-SEC23A for use in WB and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-7P5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SEC23A |
| Gene ID | 10484 |
| Uniprot ID | SC23A_HUMAN |
| Immunogen | A synthesized peptide derived from human SEC23 |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane. |
| Protein Name | Protein Transport Protein Sec23aHsec23aSec23-Related Protein A |
| Database Links | Reactome: R-HSA-1655829Reactome: R-HSA-204005Reactome: R-HSA-2132295Reactome: R-HSA-5694530Reactome: R-HSA-9705671Reactome: R-HSA-983170 |
| Cellular Localisation | Cytoplasmic VesicleCopii-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideEndoplasmic Reticulum MembraneCytoplasmCytosolEnriched At Endoplasmic Reticulum Exit SitesAlso Known As Transitional Endoplasmic Reticulum (Ter) |
| Alternative Antibody Names | Anti-Protein Transport Protein Sec23a antibodyAnti-Hsec23a antibodyAnti-Sec23-Related Protein A antibodyAnti-SEC23A antibody |
Information sourced from Uniprot.org