Anti-SEC23A antibody (Internal) (STJ71716)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SEC23A (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Horse/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 100kDa band observed in lysates of NIH3T3 (calculated MW of 86.2kDa according to Human NP_006355.2 and to Mouse NP_033173.2 ). Recommended concentration: 1-3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SEC23A |
| Gene ID | 10484 |
| Uniprot ID | SC23A_HUMAN |
| Accession Number | NP_006355.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | ANRAATTGHVID |
Additional Info
| Function | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane. |
| Protein Name | Protein Transport Protein Sec23aHsec23aSec23-Related Protein A |
| Database Links | Reactome: R-HSA-1655829Reactome: R-HSA-204005Reactome: R-HSA-2132295Reactome: R-HSA-5694530Reactome: R-HSA-9705671Reactome: R-HSA-983170 |
| Cellular Localisation | Cytoplasmic VesicleCopii-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideEndoplasmic Reticulum MembraneCytoplasmCytosolEnriched At Endoplasmic Reticulum Exit SitesAlso Known As Transitional Endoplasmic Reticulum (Ter) |
| Alternative Antibody Names | Anti-Protein Transport Protein Sec23a antibodyAnti-Hsec23a antibodyAnti-Sec23-Related Protein A antibodyAnti-SEC23A antibody |
Information sourced from Uniprot.org