Anti-SEC14L2 antibody (60-270) (STJ112600)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SEC14L2 (60-270) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEC14L2 |
| Gene ID | 23541 |
| Uniprot ID | S14L2_HUMAN |
| Immunogen Region | 60-270 |
| Immunogen Sequence | GRKVETITIIYDCEGLGLKH LWKPAVEAYGEFLCMFEENY PETLKRLFVVKAPKLFPVAY NLIKPFLSEDTRKKIMVLGA NWKEVLLKHISPDQVPVEYG GTMTDPDGNPKCKSKINYGG DIPRKYYVRDQVKQQYEHSV QISRGSSHQVEYEILFPGCV LRWQFMSDGADVGFGIFLKT KMGERQRAGEMTEVLPNQRY NSHLVPEDGTL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human SEC14L2 (NP_001191133.1). |
Additional Info
| Tissue Specificity | Widely expressed. Strong expression in liver, brain and prostate. |
| Function | Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell. |
| Protein Name | Sec14-Like Protein 2Alpha-Tocopherol-Associated ProteinTapHtapSqualene Transfer ProteinSupernatant Protein FactorSpf |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusCytoplasmic In Absence Of Alpha-TocopherolAnd Nuclear In Presence Of Alpha-Tocopherol |
| Alternative Antibody Names | Anti-Sec14-Like Protein 2 antibodyAnti-Alpha-Tocopherol-Associated Protein antibodyAnti-Tap antibodyAnti-Htap antibodyAnti-Squalene Transfer Protein antibodyAnti-Supernatant Protein Factor antibodyAnti-Spf antibodyAnti-SEC14L2 antibodyAnti-C22orf6 antibodyAnti-KIAA1186 antibodyAnti-KIAA1658 antibody |
Information sourced from Uniprot.org