Anti-SEC11A antibody [R05-6K-4] (STJA0033110)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenPeptide
General Information
| Short Description | Mouse monoclonal anti-SEC11A for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-6K-4 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Purification | Protein A |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Liquid in PBS, Glycerol and BSA |
| Storage Instruction | Store at-20°C. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SEC11A |
| Gene ID | 23478 |
| Uniprot ID | SC11A_HUMAN |
| Immunogen | Peptide |
Additional Info
| Function | Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids. |
| Protein Name | Signal Peptidase Complex Catalytic Subunit Sec11aEndopeptidase Sp18Microsomal Signal Peptidase 18 Kda SubunitSpase 18 Kda SubunitSec11 Homolog ASec11-Like Protein 1Spc18 |
| Database Links | Reactome: R-HSA-1799339Reactome: R-HSA-381771Reactome: R-HSA-400511Reactome: R-HSA-422085Reactome: R-HSA-9828806 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Signal Peptidase Complex Catalytic Subunit Sec11a antibodyAnti-Endopeptidase Sp18 antibodyAnti-Microsomal Signal Peptidase 18 Kda Subunit antibodyAnti-Spase 18 Kda Subunit antibodyAnti-Sec11 Homolog A antibodyAnti-Sec11-Like Protein 1 antibodyAnti-Spc18 antibodyAnti-SEC11A antibodyAnti-SEC11L1 antibodyAnti-SPC18 antibodyAnti-SPCS4A antibody |
Information sourced from Uniprot.org