Anti-SDHC antibody [SRM14517] (STJ11109247)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal SDHC antibody for use in WB, IF, ICC, IF-P, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IF-P/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14517 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:50000-1:200000IF/ICC, 1:800-1:4000IF-P, 1:800-1:4000IHC-P, 1:2000-1:8000ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SDHC |
| Gene ID | 6391 |
| Uniprot ID | C560_HUMAN |
| Immunogen | Synthetic peptide. This information is considered to be commercially sensitive. |
Additional Info
| Function | Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate. |
| Protein Name | Succinate Dehydrogenase Cytochrome B560 Subunit - MitochondrialIntegral Membrane Protein Cii-3Malate Dehydrogenase Quinone Cytochrome B560 SubunitQps-1Qps1Succinate Dehydrogenase Complex Subunit CSuccinate-Ubiquinone Oxidoreductase Cytochrome B Large SubunitCybl |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-71403Reactome: R-HSA-9854311 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Succinate Dehydrogenase Cytochrome B560 Subunit - Mitochondrial antibodyAnti-Integral Membrane Protein Cii-3 antibodyAnti-Malate Dehydrogenase Quinone Cytochrome B560 Subunit antibodyAnti-Qps-1 antibodyAnti-Qps1 antibodyAnti-Succinate Dehydrogenase Complex Subunit C antibodyAnti-Succinate-Ubiquinone Oxidoreductase Cytochrome B Large Subunit antibodyAnti-Cybl antibodyAnti-SDHC antibodyAnti-CYB560 antibodyAnti-SDH3 antibody |
Information sourced from Uniprot.org