Anti-SDHB antibody [BP6160] (STJA0037685)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human SDHB
General Information
| Short Description | Rabbit monoclonal anti-SDHB for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | BP6160 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SDHB |
| Gene ID | 6390 |
| Uniprot ID | SDHB_HUMAN |
| Immunogen | A synthesized peptide derived from human SDHB |
Additional Info
| Function | Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate. |
| Protein Name | Succinate Dehydrogenase Ubiquinone Iron-Sulfur Subunit - MitochondrialIron-Sulfur Subunit Of Complex IiIpMalate Dehydrogenase Quinone Iron-Sulfur Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-71403Reactome: R-HSA-9854311 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Succinate Dehydrogenase Ubiquinone Iron-Sulfur Subunit - Mitochondrial antibodyAnti-Iron-Sulfur Subunit Of Complex Ii antibodyAnti-Ip antibodyAnti-Malate Dehydrogenase Quinone Iron-Sulfur Subunit antibodyAnti-SDHB antibodyAnti-SDH antibodyAnti-SDH1 antibody |
Information sourced from Uniprot.org