Anti-SDHAF2 antibody (1-166) (STJ118644)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SDHAF2 (1-166) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SDHAF2 |
| Gene ID | 54949 |
| Uniprot ID | SDHF2_HUMAN |
| Immunogen Region | 1-166 |
| Immunogen Sequence | MAVSTVFSTSSLMLALSRHS LLSPLLSVTSFRRFYRGDSP TDSQKDMIEIPLPPWQERTD ESIETKRARLLYESRKRGML ENCILLSLFAKEHLQHMTEK QLNLYDRLINEPSNDWDIYY WATEAKPAPEIFENEVMALL RDFAKNKNKEQRLRAPDLEY LFEKPR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human SDHAF2 (NP_060311.1). |
Additional Info
| Function | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. |
| Protein Name | Succinate Dehydrogenase Assembly Factor 2 - MitochondrialSdh Assembly Factor 2Sdhaf2 |
| Database Links | Reactome: R-HSA-9854311 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Succinate Dehydrogenase Assembly Factor 2 - Mitochondrial antibodyAnti-Sdh Assembly Factor 2 antibodyAnti-Sdhaf2 antibodyAnti-SDHAF2 antibodyAnti-C11orf79 antibodyAnti-PGL2 antibodyAnti-SDH5 antibody |
Information sourced from Uniprot.org