Anti-SCYL2 antibody (STJA0007581)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SCYL2
General Information
| Short Description | Rabbit polyclonal anti-SCY1-like protein 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SCYL2 |
| Gene ID | 55681 |
| Uniprot ID | SCYL2_HUMAN |
| Immunogen | Synthesized peptide derived from human SCYL2 |
| Specificity | This antibody detects endogenous levels of SCYL2 at Human, Mouse |
Additional Info
| Function | Component of the AP2-containing clathrin coat that may regulate clathrin-dependent trafficking at plasma membrane, TGN and endosomal system (Probable). A possible serine/threonine-protein kinase toward the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine has not been confirmed. By regulating the expression of excitatory receptors at synapses, plays an essential role in neuronal function and signaling and in brain development. |
| Protein Name | Scy1-Like Protein 2Coated Vesicle-Associated Kinase Of 104 Kda |
| Database Links | |
| Cellular Localisation | Cytoplasmic VesicleClathrin-Coated VesicleGolgi ApparatusTrans-Golgi Network MembraneEndosome MembraneColocalizes To The Trans-Golgi Network (Tgn) And To Endosomal Membranes With ClathrinTransferrin And Plasma Membrane Adapter Ap1 And Ap3 Complexes |
| Alternative Antibody Names | Anti-Scy1-Like Protein 2 antibodyAnti-Coated Vesicle-Associated Kinase Of 104 Kda antibodyAnti-SCYL2 antibodyAnti-CVAK104 antibodyAnti-KIAA1360 antibody |
Information sourced from Uniprot.org