Anti-SCYL1 antibody (460-740) (STJ28818)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SCYL1 (460-740) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SCYL1 |
| Gene ID | 57410 |
| Uniprot ID | SCYL1_HUMAN |
| Immunogen Region | 460-740 |
| Immunogen Sequence | SASTRHRVLTSAFSRATRDP FAPSRVAGVLGFAATHNLYS MNDCAQKILPVLCGLTVDPE KSVRDQAFKAIRSFLSKLES VSEDPTQLEEVEKDVHAASS PGMGGAAASWAGWAVTGVSS LTSKLIRSHPTTAPTETNIP QRPTPEGVPAPAPTPVPATP TTSGHWETQEEDKDTAEDSS TADRWDDEDWGSLEQEAESV LAQQDDWSTGGQVSRASQVS NSDHKSSKSPESDWSSWEA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 460-740 of human SCYL1 (NP_065731.3). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum. Involved in the maintenance of the Golgi apparatus morphology. Isoform 6: Acts as a transcriptional activator. It binds to three different types of GC-rich DNA binding sites (box-A, -B and -C) in the beta-polymerase promoter region. It also binds to the TERT promoter region. |
| Protein Name | N-Terminal Kinase-Like ProteinCoated Vesicle-Associated Kinase Of 90 KdaScy1-Like Protein 1Telomerase Regulation-Associated ProteinTelomerase Transcriptional Element-Interacting FactorTeratoma-Associated Tyrosine Kinase |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeEndoplasmic Reticulum-Golgi Intermediate CompartmentGolgi ApparatusCis-Golgi NetworkLocalized To The Endoplasmic Reticulum-Golgi Intermediate And Cis-Golgi In An Arf1-Independent MannerIsoform 1: CytoplasmCytoplasmic Throughout The Cell CycleIsoform 2: CytoplasmIsoform 3: CytoplasmCytoplasmic During Interphase And Centrosomal During MitosisIt Localizes To The Centrosomes In A Microtubule-Independent MannerIsoform 6: Nucleus |
| Alternative Antibody Names | Anti-N-Terminal Kinase-Like Protein antibodyAnti-Coated Vesicle-Associated Kinase Of 90 Kda antibodyAnti-Scy1-Like Protein 1 antibodyAnti-Telomerase Regulation-Associated Protein antibodyAnti-Telomerase Transcriptional Element-Interacting Factor antibodyAnti-Teratoma-Associated Tyrosine Kinase antibodyAnti-SCYL1 antibodyAnti-CVAK90 antibodyAnti-GKLP antibodyAnti-NTKL antibodyAnti-TAPK antibodyAnti-TEIF antibodyAnti-TRAP antibodyAnti-HT019 antibody |
Information sourced from Uniprot.org