Anti-SCP1 antibody (STJ13100379)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from human SCP1 conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SCP1 for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SYCP1 |
| Gene ID | 6847 |
| Uniprot ID | SYCP1_HUMAN |
| Immunogen | A synthetic peptide from human SCP1 conjugated to blue carrier protein was used as the antigen. |
| Specificity | Specific for SCP1. |
Additional Info
| Function | Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility. |
| Protein Name | Synaptonemal Complex Protein 1Scp-1Cancer/Testis Antigen 8Ct8 |
| Database Links | Reactome: R-HSA-1221632 |
| Cellular Localisation | NucleusChromosomeCentromereIn Tripartite Segments Of Synaptonemal ComplexesBetween Lateral Elements In The NucleusIts N-Terminus Is Found Towards The Center Of The Synaptonemal Complex While The C-Terminus Extends Well Into The Lateral Domain Of The Synaptonemal ComplexOnly Rarely Detected At Centromeres During Leptotene And ZygoteneDetected At Centromeres During Mid-DiploteneWhen It Is No Longer Present Along Chromosome ArmsNo Longer Detected At Centromeres At Later Stages Of Meiosis |
| Alternative Antibody Names | Anti-Synaptonemal Complex Protein 1 antibodyAnti-Scp-1 antibodyAnti-Cancer/Testis Antigen 8 antibodyAnti-Ct8 antibodyAnti-SYCP1 antibodyAnti-SCP1 antibody |
Information sourced from Uniprot.org