• Immunohistochemistry analysis of paraffin-embedded Rat ovary using SCO2 Rabbit polyclonal antibody (STJ29131) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded Human colon using SCO2 Rabbit polyclonal antibody (STJ29131) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using SCO2 antibody (STJ29131) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 3min.

Anti-SCO2 antibody (100-266) (STJ29131)

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STJ29131

£169.50 - £449.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SCO2 (100-266) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SCO2
Gene ID: 9997
Uniprot ID: SCO2_HUMAN
Immunogen Region: 100-266
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-266 of human SCO2 (NP_005129.2).
Immunogen Sequence: GQGDFHLLDHRGRARCKADF RGQWVLMYFGFTHCPDICPD ELEKLVQVVRQLEAEPGLPP VQPVFITVDPERDDVEAMAR YVQDFHPRLLGLTGSTKQVA QASHSYRVYYNAGPKDEDQD YIVDHSIAIYLLNPDGLFTD YYGRSRSAEQISDSVRRHMA AFRSVLS
Tissue Specificity Ubiquitous.
Function Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
Protein Name Protein Sco2 Homolog - Mitochondrial
Database Links Reactome: R-HSA-5628897
Reactome: R-HSA-611105
Reactome: R-HSA-9707564
Cellular Localisation Mitochondrion Inner Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Protein Sco2 Homolog - Mitochondrial antibody
Anti-SCO2 antibody

Information sourced from Uniprot.org

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