| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SCN4B (80-228) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Scn4b |
| Gene ID: |
399548 |
| Uniprot ID: |
SCN4B_MOUSE |
| Immunogen Region: |
80-228 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 80-228 of mouse SCN4B (Q7M729). |
| Immunogen Sequence: |
IDGIVKNDKSDPKVRVKDDD RITLEGSTKEKTNNISILLS DLEFSDTGRYTCFVRNPKEK DLNNSATIFLQVVDKLEKVD NTVTLIILAVVGGVIGLLVC ILLLKKLITFILKKTREKKK ECLVSSSGNDNTENGLPGSK AEEKPPTKV |
| Post Translational Modifications | Contains an interchain disulfide bond with SCN2A. N-glycosylated. |
| Function | Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom. |
| Protein Name | Sodium Channel Subunit Beta-4 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sodium Channel Subunit Beta-4 antibodyAnti-Scn4b antibodyAnti-Gm1471 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
