• Western blot analysis of lysates from HepG2 and Jurkat cells, using SCN4B Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HeLa cells using SCN4B antibody.
  • Western blot analysis of various cells using Scn4b Polyclonal Antibody

Anti-SCN4B antibody (61-110 aa) (STJ95589)

SKU:
STJ95589

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Sodium channel subunit beta-4 (61-110 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SCN4B
Gene ID: 6330
Uniprot ID: SCN4B_HUMAN
Immunogen Region: 61-110 aa
Specificity: Scn4b Polyclonal Antibody detects endogenous levels of Scn4b protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human SCN4B at the amino acid range 61-110
Post Translational Modifications Contains an interchain disulfide bond with SCN2A. N-glycosylated.
Function Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.
Protein Name Sodium Channel Subunit Beta-4
Database Links Reactome: R-HSA-445095
Reactome: R-HSA-5576892
Reactome: R-HSA-9717207
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Sodium Channel Subunit Beta-4 antibody
Anti-SCN4B antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance