Anti-SCD5 antibody (1-75) (STJ115093)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SCD5 (1-75) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SCD5 |
| Gene ID | 79966 |
| Uniprot ID | SCD5_HUMAN |
| Immunogen Region | 1-75 |
| Immunogen Sequence | MPGPATDAGKIPFCDAKEEI RAGLESSEGGGGPERPGARG QRQNIVWRNVVLMSLLHLGA VYSLVLIPKAKPLTL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human SCD5 (NP_001032671.2). |
Additional Info
| Tissue Specificity | Detected in fetal brain, and at lower levels in fetal kidney. Detected in adult brain and pancreas, and at lower levels in kidney and lung. Expressed in spiral ganglion cells and the organ of Corti of fetal cochlea. |
| Function | Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Involved in neuronal cell proliferation and differentiation through down-regulation of EGFR/AKT/MAPK and Wnt signaling pathways. |
| Protein Name | Stearoyl-Coa Desaturase 5Acyl-Coa-Desaturase 4Hscd5Stearoyl-Coa 9-DesaturaseStearoyl-Coa Desaturase 2 |
| Database Links | Reactome: R-HSA-75105Reactome: R-HSA-9619665Reactome: R-HSA-9841922 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Stearoyl-Coa Desaturase 5 antibodyAnti-Acyl-Coa-Desaturase 4 antibodyAnti-Hscd5 antibodyAnti-Stearoyl-Coa 9-Desaturase antibodyAnti-Stearoyl-Coa Desaturase 2 antibodyAnti-SCD5 antibodyAnti-ACOD4 antibodyAnti-SCD2 antibodyAnti-SCD4 antibody |
Information sourced from Uniprot.org