Anti-SCAP2/PRAP antibody (C-Term) (STJ70135)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SCAP2/PRAP (C-Term) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications. |
| Applications | Pep-ELISA/WB/IF/FC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:3000.WB: Approx. 26+37kDa bands observed in lysates of cell line K562, and approx. 28+38kDa in preliminary testing of U937 cell lysate (calculated MW of 21.6kDa according to NP_001290397.1 and 4 |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SKAP2 |
| Gene ID | 8935 |
| Uniprot ID | SKAP2_HUMAN |
| Accession Number | NP_003921.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | GLVPKAYIMEMYDI |
Additional Info
| Post Translational Modifications | Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22. |
| Function | May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway. |
| Protein Name | Src Kinase-Associated Phosphoprotein 2Pyk2/Raftk-Associated ProteinRetinoic Acid-Induced Protein 70Skap55 HomologSkap-55homSkap-HomSrc Family-Associated Phosphoprotein 2Src Kinase-Associated Phosphoprotein 55-Related ProteinSrc-Associated Adapter Protein With Ph And Sh3 Domains |
| Database Links | Reactome: R-HSA-391160 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Src Kinase-Associated Phosphoprotein 2 antibodyAnti-Pyk2/Raftk-Associated Protein antibodyAnti-Retinoic Acid-Induced Protein 70 antibodyAnti-Skap55 Homolog antibodyAnti-Skap-55hom antibodyAnti-Skap-Hom antibodyAnti-Src Family-Associated Phosphoprotein 2 antibodyAnti-Src Kinase-Associated Phosphoprotein 55-Related Protein antibodyAnti-Src-Associated Adapter Protein With Ph And Sh3 Domains antibodyAnti-SKAP2 antibodyAnti-PRAP antibodyAnti-RA70 antibodyAnti-SAPS antibodyAnti-SCAP2 antibodyAnti-SKAP55R antibody |
Information sourced from Uniprot.org