Anti-SAMSN1 antibody (N-Term) (STJ70586)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SAMSN1 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 48kDa band observed in Jurkat Tcell lysate (calculated MW of 41.7kDa according to NP_071419.2). The observed size is consistent with observations with competing products. Recomm |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SAMSN1 |
| Gene ID | 64092 |
| Uniprot ID | SAMN1_HUMAN |
| Accession Number | NP_071419.2 |
| Immunogen Region | N-Term |
| Immunogen Sequence | IRLDTLSASLGRSC |
| Specificity | Please note that the immunogen sequence is present in NP_071419.2 (and in AAK07746) but is no longer present in the latest reference sequence (NP_071419.3 at 05/10/05). This latest version has not been subject to final review by NCBI. This antibody m |
Additional Info
| Function | Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation. |
| Protein Name | Sam Domain-Containing Protein Samsn-1Hematopoietic Adaptor Containing Sh3 And Sam Domains 1Nash1Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1Sh3-Sam Adaptor Protein |
| Cellular Localisation | NucleusCytoplasmCell ProjectionRuffleShuttles Between Cytoplasm And NucleusColocalizes With The Actin Cytoskeleton And Actin-Rich Membrane Ruffles |
| Alternative Antibody Names | Anti-Sam Domain-Containing Protein Samsn-1 antibodyAnti-Hematopoietic Adaptor Containing Sh3 And Sam Domains 1 antibodyAnti-Nash1 antibodyAnti-Sam Domain - Sh3 Domain And Nuclear Localization Signals Protein 1 antibodyAnti-Sh3-Sam Adaptor Protein antibodyAnti-SAMSN1 antibodyAnti-HACS1 antibody |
Information sourced from Uniprot.org