Anti-SAMD9 antibody (84-189 aa) [R09-5B4] (STJA0011932)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human SAMD9
STJA0011932-100
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General Information

Short DescriptionRabbit monoclonal anti-SAMD9 (84-189 aa) for use in WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ICC/IF
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDR09-5B4
IsotypeIgG
ConjugationUnconjugated
Concentration0.3 mg/mL
PurificationAffinity Purified
Dilution RangeWB 1:500-1:1000
IF 1:50-1:200
Formulation50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene SymbolSAMD9
Gene ID54809
Uniprot IDSAMD9_HUMAN
ImmunogenA synthetic peptide of human SAMD9
Immunogen Region84-189 aa

Additional Info

Tissue Specificity Widely expressed. Very low levels are detected in skeletal muscle. Not detected in brain. Down-regulated in aggressive fibromatosis, as well as in breast and colon cancers. Up-regulated in fibroblasts from patients with normophosphatemic tumoral calcinosis (NFTC).
Function Double-stranded nucleic acid binding that acts as an antiviral factor by playing an essential role in the formation of cytoplasmic antiviral granules. May play a role in the inflammatory response to tissue injury and the control of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2. May be involved in endosome fusion.
Protein Name Sterile Alpha Motif Domain-Containing Protein 9
Sam Domain-Containing Protein 9
Database Links
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Sterile Alpha Motif Domain-Containing Protein 9 antibody
Anti-Sam Domain-Containing Protein 9 antibody
Anti-SAMD9 antibody
Anti-C7orf5 antibody
Anti-DRIF1 antibody
Anti-KIAA2004 antibody
Anti-OEF1 antibody

Information sourced from Uniprot.org

Citations

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