Anti-SALL4 antibody (700-800 aa) [ABT-SALL4] (STJ197004)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenSynthesized peptide derived from the human SALL4 at the amino acid range 700-800
General Information
| Short Description | Mouse monoclonal anti-Sal-like protein 4 (700-800 aa) for use in IHC, IF and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ABT-SALL4 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC-P 1:50-100IF 1:50-100WB 1:100-1000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SALL4 |
| Gene ID | 57167 |
| Uniprot ID | SALL4_HUMAN |
| Immunogen | Synthesized peptide derived from the human SALL4 at the amino acid range 700-800 |
| Immunogen Region | 700-800 aa |
| Specificity | This antibody detects endogenous levels of human SALL4. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section |
Additional Info
| Post Translational Modifications | Isoform SALL4B exists primarily as a ubiquitinated form. Sumoylation with both SUMO1 and SUMO2 regulates the stability, subcellular localization, transcriptional activity, and may reduce interaction with POU5F1/OCT4. |
| Function | Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. |
| Protein Name | Sal-Like Protein 4Zinc Finger Protein 797Zinc Finger Protein Sall4 |
| Database Links | Reactome: R-HSA-2892247Reactome: R-HSA-452723Reactome: R-HSA-8943724 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Sal-Like Protein 4 antibodyAnti-Zinc Finger Protein 797 antibodyAnti-Zinc Finger Protein Sall4 antibodyAnti-SALL4 antibodyAnti-ZNF797 antibody |
Information sourced from Uniprot.org