Anti-S6K2 antibody [R06-5O2] (STJA0036854)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human P70 S6 Kinase beta
General Information
| Short Description | Rabbit monoclonal anti-S6K2 for use in WB, IHC-P, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-5O2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | RPS6KB2 |
| Gene ID | 6199 |
| Uniprot ID | KS6B2_HUMAN |
| Immunogen | A synthesized peptide derived from human P70 S6 Kinase beta |
Additional Info
| Post Translational Modifications | Phosphorylated and activated by MTOR. Phosphorylation by PKC within the NLS in response to mitogenic stimuli causes cytoplasmic retention. |
| Function | Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7. |
| Protein Name | Ribosomal Protein S6 Kinase Beta-2S6k-Beta-2S6k270 Kda Ribosomal Protein S6 Kinase 2P70s6k2P70-S6k 2S6 Kinase-Related KinaseSrkSerine/Threonine-Protein Kinase 14bP70 Ribosomal S6 Kinase BetaS6k-BetaP70 S6 Kinase BetaP70 S6k-BetaP70 S6kbP70-Beta |
| Database Links | Reactome: R-HSA-198693Reactome: R-HSA-5674400 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Ribosomal Protein S6 Kinase Beta-2 antibodyAnti-S6k-Beta-2 antibodyAnti-S6k2 antibodyAnti-70 Kda Ribosomal Protein S6 Kinase 2 antibodyAnti-P70s6k2 antibodyAnti-P70-S6k 2 antibodyAnti-S6 Kinase-Related Kinase antibodyAnti-Srk antibodyAnti-Serine/Threonine-Protein Kinase 14b antibodyAnti-P70 Ribosomal S6 Kinase Beta antibodyAnti-S6k-Beta antibodyAnti-P70 S6 Kinase Beta antibodyAnti-P70 S6k-Beta antibodyAnti-P70 S6kb antibodyAnti-P70-Beta antibodyAnti-RPS6KB2 antibodyAnti-STK14B antibody |
Information sourced from Uniprot.org