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Anti-S100P antibody [16/f5] (STJ16100449)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal anti-S100P for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 16/f5 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Dilution Range | IHC-P 1:100-1:500 |
| Formulation | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | S100P |
| Gene ID | 6286 |
| Uniprot ID | S100P_HUMAN |
Additional Info
| Tissue Specificity | Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. |
| Function | May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE). |
| Protein Name | Protein S100-PMigration-Inducing Gene 9 ProteinMig9Protein S100-ES100 Calcium-Binding Protein P |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmCell ProjectionMicrovillus MembraneColocalizes With S100pbp In The NucleusColocalizes With Ezr In The Microvilli In A Calcium-Dependent Manner |
| Alternative Antibody Names | Anti-Protein S100-P antibodyAnti-Migration-Inducing Gene 9 Protein antibodyAnti-Mig9 antibodyAnti-Protein S100-E antibodyAnti-S100 Calcium-Binding Protein P antibodyAnti-S100P antibodyAnti-S100E antibody |
Information sourced from Uniprot.org