Anti-S100A6 antibody (1-90) [S4MR] (STJ11101874)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal S100 alpha 6 (1-90) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | S100A6 |
| Gene ID | 6277 |
| Uniprot ID | S10A6_HUMAN |
| Immunogen Region | 1-90 |
| Immunogen Sequence | MACPLDQAIGLLVAIFHKYS GREGDKHTLSKKELKELIQK ELTIGSKLQDAEIARLMEDL DRNKDQEVNFQEYVTFLGAL ALIYNEALKG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human S100A6 (P06703). |
Additional Info
| Post Translational Modifications | The N-terminus is blocked. |
| Function | May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. |
| Protein Name | Protein S100-A6CalcyclinGrowth Factor-Inducible Protein 2a9Mln 4Prolactin Receptor-Associated ProteinPraS100 Calcium-Binding Protein A6 |
| Database Links | |
| Cellular Localisation | Nucleus EnvelopeCytoplasmCell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Protein S100-A6 antibodyAnti-Calcyclin antibodyAnti-Growth Factor-Inducible Protein 2a9 antibodyAnti-Mln 4 antibodyAnti-Prolactin Receptor-Associated Protein antibodyAnti-Pra antibodyAnti-S100 Calcium-Binding Protein A6 antibodyAnti-S100A6 antibodyAnti-CACY antibody |
Information sourced from Uniprot.org