Anti-S100A3 antibody (1-101) (STJ25430)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal S100A3 (1-101) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | S100A3 |
| Gene ID | 6274 |
| Uniprot ID | S10A3_HUMAN |
| Immunogen Region | 1-101 |
| Immunogen Sequence | MARPLEQAVAAIVCTFQEYA GRCGDKYKLCQAELKELLQK ELATWTPTEFRECDYNKFMS VLDTNKDCEVDFVEYVRSLA CLCLYCHEYFKDCPSEPPCS Q |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A3 (NP_002951.1). |
Additional Info
| Tissue Specificity | Skin specific, specifically expressed at the inner endocuticle of hair fibers. |
| Post Translational Modifications | More than half of the arginine residues undergo citrullination by PAD1 and PAD2. Arg-51 is specifically citrullinated by PAD3 and promotes tetramerization. |
| Function | Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation. |
| Protein Name | Protein S100-A3Protein S-100eS100 Calcium-Binding Protein A3 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein S100-A3 antibodyAnti-Protein S-100e antibodyAnti-S100 Calcium-Binding Protein A3 antibodyAnti-S100A3 antibodyAnti-S100E antibody |
Information sourced from Uniprot.org