Anti-S100A16 antibody (1-103) (STJ118607)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal S100A16 (1-103) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | S100A16 |
| Gene ID | 140576 |
| Uniprot ID | S10AG_HUMAN |
| Immunogen Region | 1-103 |
| Immunogen Sequence | MSDCYTELEKAVIVLVENFY KYVSKYSLVKNKISKSSFRE MLQKELNHMLSDTGNRKAAD KLIQNLDANHDGRISFDEYW TLIGGITGPIAKLIHEQEQQ SSS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-103 of human S100A16 (NP_525127.1). |
Additional Info
| Tissue Specificity | Ubiquitous. Highly expressed in esophagus, adipose tissues and colon. Expressed at lower level in lung, brain, pancreas and skeletal muscle. Expression is up-regulated in tumors of bladder, lung, thyroid gland, pancreas and ovary. Expressed in astrocytes. |
| Function | Calcium-binding protein. Binds one calcium ion per monomer. Can promote differentiation of adipocytes (in vitro). Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake. |
| Protein Name | Protein S100-A16Aging-Associated Gene 13 ProteinProtein S100-FS100 Calcium-Binding Protein A16 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusCytoplasmPrimarily NucleolarA High Intracellular Calcium Level Induces Nucleolar Exit And Nucleocytoplasmic TransportWhereas A Low Intracellular Calcium Level Leads To Nuclear Translocation And Accumulation Within Specific Region Of Nucleoli |
| Alternative Antibody Names | Anti-Protein S100-A16 antibodyAnti-Aging-Associated Gene 13 Protein antibodyAnti-Protein S100-F antibodyAnti-S100 Calcium-Binding Protein A16 antibodyAnti-S100A16 antibodyAnti-S100F antibodyAnti-AAG13 antibody |
Information sourced from Uniprot.org