| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-S100A16 (1-103) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
S100A16 |
| Gene ID: |
140576 |
| Uniprot ID: |
S10AG_HUMAN |
| Immunogen Region: |
1-103 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-103 of human S100A16 (NP_525127.1). |
| Immunogen Sequence: |
MSDCYTELEKAVIVLVENFY KYVSKYSLVKNKISKSSFRE MLQKELNHMLSDTGNRKAAD KLIQNLDANHDGRISFDEYW TLIGGITGPIAKLIHEQEQQ SSS |
| Tissue Specificity | Ubiquitous. Highly expressed in esophagus, adipose tissues and colon. Expressed at lower level in lung, brain, pancreas and skeletal muscle. Expression is up-regulated in tumors of bladder, lung, thyroid gland, pancreas and ovary. Expressed in astrocytes. |
| Function | Calcium-binding protein. Binds one calcium ion per monomer. Can promote differentiation of adipocytes (in vitro). Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake. |
| Protein Name | Protein S100-A16Aging-Associated Gene 13 ProteinProtein S100-FS100 Calcium-Binding Protein A16 |
| Cellular Localisation | NucleusNucleolusCytoplasmPrimarily NucleolarA High Intracellular Calcium Level Induces Nucleolar Exit And Nucleocytoplasmic TransportWhereas A Low Intracellular Calcium Level Leads To Nuclear Translocation And Accumulation Within Specific Region Of Nucleoli |
| Alternative Antibody Names | Anti-Protein S100-A16 antibodyAnti-Aging-Associated Gene 13 Protein antibodyAnti-Protein S100-F antibodyAnti-S100 Calcium-Binding Protein A16 antibodyAnti-S100A16 antibodyAnti-S100F antibodyAnti-AAG13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
